Halomonas elongata Moderately Halophilic Eubacterium, for Ectoine as a Compatible Solute in a Characterization of Biosynthetic Enzymes
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Characterization of biosynthetic enzymes for ectoine as a compatible solute in a moderately halophilic eubacterium, Halomonas elongata.
1,4,5,6-Tetrahydro-2-methyl-4-pyrimidinecarboxylic acid (ectoine) is an excellent osmoprotectant. The biosynthetic pathway of ectoine from aspartic beta-semialdehyde (ASA), in Halomonas elongata, was elucidated by purification and characterization of each enzyme involved. 2,4-Diaminobutyrate (DABA) aminotransferase catalyzed reversively the first step of the pathway, conversion of ASA to DABA b...
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The halophilic γ-proteobacterium Halomonas elongata DSM 2581(T) thrives at high salinity by synthesizing and accumulating the compatible solute ectoine. Ectoine levels are highly regulated according to external salt levels but the overall picture of its metabolism and control is not well understood. Apart from its critical role in cell adaptation to halophilic environments, ectoine can be used ...
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Halophilic microorganisms cope with environmental stresses by producing and accumulating compatible solutes. Ectoine is one of the most important members of compatible solutes which have extra protective properties compared to other compatible solutes. Ectoine attracts several scientific and commercial attention because of their multiple industrial applications. This brief review presents appli...
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A new family, the Hafomonadaceae, has recently been proposed for members of the genera Deleya and Halornonas. The three strains investigated, Deleya haiuphila, Halomonas elongata and Flavobacterium halmephilum (reclassified as H. hahophila), are aerobic heterotrophic micro-organisms exhibiting an extreme salt tolerance. The major organic osmoregulatory solutes of these organisms were examined u...
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The osmoregulatory pathways of the moderately halophilic bacterium Halomonas elongata DSM 3043 have been investigated. This strain grew optimally at 1.5 to 2 M NaCl in M63 glucose-defined medium. It required at least 0.5 M NaCl for growth, which is a higher concentration than that exhibited by the H. elongata type strain ATCC 33173. Externally provided betaine, choline, or choline-O-sulfate (bu...
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تاریخ انتشار 1998